Staff and specialities
Professor: Yoshihiro TAKEUCHI
Pediatric Neurology, Develpomental Biology, Epileptology
Associate Professor: Tomoyuki TAKANO
Pediatric Neurology
Associate Professor: Takashi TAGA
Pediatric Hematology and Oncology
Associate Professor: Yoshihiro MARUO
Endocrinology and Metabolism
Senior Assistant Professor: Shigeki KOSHIDA
Neonatology
Assistant Professor: Katsuyuki MATSUI
Endocrinology and Metabolism
Assistant Professor: Toshihiro SAWAI
Pediatric Nephrology
Assistant Professor: Takahide YANAGI
Neonatology
Assistant Professor: Chihiro SAWAI
Developmental Disorders
Assistant Professor: Yuko SAKAUE
Developmental Disorders
Assistant Professor: Seiichiro YOSHIOKA
Pediatric Neurology
Assistant Professor: Junpei SOUMURA
Pediatric Cardiology
Assistant Professor: Ohki FURUKAWA
Pediatric Cardiology
Assistant Professor: Sayuri NAKAHARA
Neonatology
Assistant Professor: Akitaka NOMURA
Pediatric Hematology and Oncology
Assistant Professor: Noriko NISHIKURA
Pediatric Neurology
Outline of the department
1) Neurology Group:
Our research work has been focused on the following subjects: pathogenesis of
CNS malformations, neuronal plasticity after CNS damage, metabolic basis of
neurodegenarative disorders, and seizure susceptibility in malformed brains.
Seizure disorders, motor neuron diseases and developmental disorders including
ADHD (attention deficit / hyperactivity disorders) are also clinically
investigated.
2) Endocrinology and Metabolism Group:
Gene abnormalities in congenital metabolic disorders are investigated using
molecular biology techniques. The enzymes related to drug metabolism and SNPs
on Gilbert's syndrome among Japanese are also investigated.
3) Hematology and Oncology Group:
Acute lymphoblastic and myeloblastic leukemias in childhood are treated with
CCLSG (Children Cancer Leukemia Study Group) protocols using MRD (Minimum
residual disease) assay. For children suffering refractory leukemias, solid
tumors including neuroblastoma, Ewing's tumor, brain tumors and so on, or
severe aplastic anemias are treated with alloBMT(bone marrow transplantation),
auto/allo PBSCT or allo CBSCT(Cord Blood Stem Cell Transplantation).
Hemophlias are also treated with supplement therapy of coagulation factor.
Basic research on childhood malignant neoplasms has been conducted. Especially
phenotypic study on malignant rhabdoid tumor are investigated.
4) Cardiology Group:
The etiology and morphogenesis of congenital heart diseases are investigated
using experimental models with immunohistochemical and molecular biology
technique. The development of coronary arteries is also studied comparing the
normal and malformed heart. Interventional catheterization, including balloon
valvuloplasty, angioplasty and coil embolization, is performed on the patients
with pre- and post-operative congenital heart disease. Respiratory management
with nitrogen gas is provided to the patients with serious congenital heart
disease before cardiac surgery in order to control the pulmonary blood flow.
5) Neonatology Group:
We have a neonatal intensive care unit (NICU) and accommodate the premature
baby and the high risk newborn baby of the most serious illness of the area by
the 24-hour system. We are managing the neonatal bed availability information
system with FAX and the Internet, which cooperated with Shiga Prefecture as
the member of Shiga Neonatal Mutual Cooperating Group (NMCG). We are doing NO
(nitric oxide) inhalation therapy as the advanced medical care to newborn baby
with persistent pulmonary hypertension of newborn. As the member of Neonatal
Research Network Japan (NRN), we develop and are managing the nationwide
newborn baby clinical research support system using the Internet.
6) Allergy Group:
Asthma, atopic dermatitis and food allergy are treated.
7) Nephrology Group:
Various childhood renal diseases are treated and renal biopsy is routinely
performed.
