Publication List (2017/4/8 現在)

英文原著

1. Ikawa T*, MasudaK, Endo TA, Endo M, Isono K, Koseki Y, Nakagawa R, Kometani K, Takano J, Agata Y, Katsura Y, Kurosaki T, Vidal M, Koseki H, Kawamoto H*
Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of B lineage program.
Genes Dev. 30, 2475-2485 (2016)


2. Tomita K, Tanaka H, Kageyama S, Nagasawa M, Wada A, Murai R, Kobayashi K, Hanada E, Agata Y, Kawauchi A.
The Effect of D-Aspartate on Spermatogenesis in Mouse Testis.
Biol Reprod. 94(2): 30, 1-7 (2016)


3. Ikawa T, Masuda K, Huijskens M.J.A.J., Satoh R, Kakugawa K, Agata Y, Miyai T, Germeraad W.T.V., Katsura Y, Kawamoto H.
Induced Developmental Arrest of Early Hematopoietic Progenitors Leads to the Generation of Leukocyte Stem Cells.
Stem Cell Reports 5, 716-727 (2015) doi:10.1016/j.stemcr.2015.09.012

4. Miyazaki M, Miyazaki K, Chen S, Chandra V, Wagatsuma K, Agata Y,
Rodewald HR, Saito R, Chang AN, Varki N, Kawamoto H, Murre C.
The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways
to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.
Genes Dev. 29(4), 409-25 (2015)

5.
Doi K, Imai T, Kressler C, Yagita H, Agata Y, Vooijs M, Hamazaki Y, Inoue J, Minato N.
Crucial role of the Rap G protein signal in Notch activation and leukemogenicity
of T-cell acute lymphoblastic leukemia.
Sci Rep. 5, 7987 (2015)

6. Suzuki C, Tanigawa M, Tanaka H, Horiike K, Kanekatsu R, Tojo M, Nagata Y.
Effect of
D-serine on spermatogenesis and extracellular signal-regulated protein kinase (ERK) phosphorylation in the testis of the silkworm, Bombyx mori.
J Insect Physiol. 67, 97-104 (2014)

7. Maezawa T,
Tanaka H, Nakagawa H, Ono M, Aoki M, Matsumoto M, Ishida T, Horiike K, Kobayashi K.
Planarian
D-amino acid oxidase is involved in ovarian development during sexual induction.
Mech. Dev. 132, 69-78 (2014)

8. Nishimura Y,
Tanaka H, Ishida T, Imai S, Matsusue Y, Agata Y, Horiike K.
Immunohistochemical localization of
D-serine dehydratase in chicken tissues.
Acta Histochem. S0065-1281(13)00244-4 (2014).

9. Sato T, Chiba T, Ohno S, Sato C, Sugoh T, Miyashita K, Akatsuka H, Hozumi K, Okada Y, Iida Y, Akatsuka A,
Agata Y, Chiba M, Kohu K, Satake M, Tanabe H, Saya H, Habu S.
Reciprocal control of G1-phase progression is required for Th-POK/Runx3-mediated CD4/8 thymocyte cell fate decision.
J Immunol. 189, 4426-4436 (2012)

10. Higuchi T, Sakamoto S, Kakinuma Y, Kai S, Yagyu K, Todaka H, Chi E, Okada S, Ujihara T, Morisawa K, Ono M, Sugiyama Y, Ishida W, Fukushima A, Tsuda M,
Agata Y, Taniguchi T.
High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles.
PLoS One 7(8):e43340 (2012)

11. Sakamoto S, Wakae K,
Anzai Y, Murai K, Tamaki N, Miyazaki M, Miyazaki K, Romanow WJ, Ikawa T, Kitamura D, Yanagihara I, Minato N, Murre C, Agata Y. (corresponding author)
E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus.
J Immunol. 188, 5547-5560 (2012)

12. Kawamata T, Lu J, Sato T, Tanaka M, Nagaoka H,
Agata Y, Toyoshima T, Yokoyama K, Oyaizu N, Nakamura N, Ando K, Tojo A and Kotani A.
Imatinib mesylate directly impairs class switch recombination through downregulation of AID.
Blood 119, 3123-3127 (2012)

13. Miyazaki M, Rivera RR, Miyazaki K, Lin YC,
Agata Y, Murre C.
The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells.
Nat Immunol., 12, 992-1001 (2011)

14. Nozaki M, Wakae K, Tamaki N, Sakamoto S, Ohnishi K, Uejima T, Minato N, Yanagihara I,
Agata Y. (corresponding author)
Regulation of TCR Vγ2 gene rearrangement by the helix-loop-helix protein, E2A.
Int Immunol., 23, 297-305 (2011)

15. Kawai Y, Hamazaki Y, Fujita H, Fujita A, Sato T, Furuse M, Fujimoto T, Jetten AM,
Agata Y, Minato N.
Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency.
Proc Natl Acad Sci U S A., 108, 4075-4080 (2011)

16.
Tanaka H, Senda M, Nagarajan V, Yamamoto A, Senda T, Ishida T, Horiike K.
Crystal structure of a zinc-dependent
D-serine dehydratase from chicken kidney.
J. Biol. Chem., 286, 27548-27558 (2011)

17. Senda M,
Tanaka H, Ishida T, Horiike K, Senda T.
Crystallization and preliminary crystallographic analysis of
D-serine dehydratase from chicken kidney.
Acta Crystallogr Sect F Struct Biol Cryst Commun, 67, 147-149 (2011)

18. Suzuki C, Murakami M, Yokobori H,
Tanaka H, Ishida T, Horiike K, Nagata Y.
Rapid determination of free D-serine with chicken D-serine dehydratase.
J Chromatogr B Analyt Technol Biomed Life Sci, 879, 3326-3330 (2011)

19. Yamamoto A,
Tanaka H, Ishida T, Horiike K.
Immunohistochemical localization of D-aspartate oxidase in porcine peripheral tissues.
Amino Acids, 41, 529-536 (2011)

20. Yamamoto A,
Tanaka H, Ishida T, Horiike K.
D-Aspartate oxidase localization in pituitary and pineal glands of the female pig.
J. Neuroendocrinol., 22, 1165-1172 (2010)

21. Sakamoto S, Aoki K, Higuchi T, Todaka H, Morisawa K, Tamaki N, Hatano E, Fukushima A, Taniguchi T,
Agata Y.
The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway.
Mol. Cell. Biol., 29, 3754-3769 (2009)

22. Kitao H, Kimura M, Yamamoto K, Seo H, Namikoshi K,
Agata Y, Ohta K, Takata M.
Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.
Int. Immunol., 20, 277-284 (2008)

23.
Tanaka H, Yamamoto A, Ishida T, Horiike K.
D-Serine dehydratase from chicken kidney: a vertebral homologue of the cryptic enzyme from Burkholderia cepacia.
J. Biochem., 143, 49-57, (2008)

24.
Agata Y, Tamaki N, Ikawa T, Masuda K, Sakamoto S, Kawamoto H, Murre C. (corresponding author)
Regulation of T Cell Receptor β Gene Rearrangements and Allelic Exclusion by the Helix-Loop-Helix Protein, E47.
Immunity, 27, 871-884 (2007)

25. Katakai T, Nomura T, Gonda H, Sugai M,
Agata Y, Nishio A, Masuda T, Sakaguchi S, Shimizu A.
Spontaneous Large-scale Lymphoid Neogenesis and Balanced Autoimmunity versus Tolerance in the Stomach of H+/K+-ATPase-reactive TCR Transgenic Mouse.
J. Immunol., 177, 7858-7867 (2006)

26. Murai K, Naruse Y, Shaul Y,
Agata Y, Mori N.
Direct interaction of NRSF with TBP: chromatin reorganization and core promoter repression for neuron-specific gene transcription.
Nucleic Acids Res., 32, 3180-3189 (2004)

27. Nambu Y, Sugai M, Gonda H, Lee CG, Katakai T,
Agata Y, Yokota Y, Shimizu A.
Transcription-coupled events associating with immunoglobulin switch region chromatin.
Science, 302, 2137-2140 (2003)

28. Gonda H, Sugai M, Nambu Y, Katakai T,
Agata Y, Mori KJ, Yokota Y, Shimizu A.
The balance between Pax5 and Id2 activities is the key to AID gene expression.
J. Exp. Med., 198, 1427-1437 (2003)

29. Sayegh CE, Quong MW,
Agata Y, Murre C.
E-proteins directly regulate expression of activation-induced deaminase in mature B cells.
Nat. Immunol., 4, 586-593 (2003)

30. Katakai T, Hara T, Sugai M, Gonda H, Nambu Y, Matsuda E,
Agata Y, Shimizu A.
Chemokine-independent preference of T-helper-1 cells in transendothelial migration.
J. Biol. Chem., 277, 50948-50958 (2002)

31. Ye SK,
Agata Y, Lee HC, Kurooka H, Kitamura T, Shimizu A, Honjo T, Ikuta K.
The IL-7 receptor controls the accessibility of the TCRγ locus by Stat5 and histone acetylation.
Immunity, 15, 813-823 (2001)

32.
Agata Y, Katakai T, Ye SK, Sugai M, Gonda H, Honjo T, Ikuta K, Shimizu A. (corresponding author)
Histone acetylation determines the developmentally regulated accessibility for T cell receptor γ gene recombination.
J. Exp. Med., 193, 873-880 (2001)

33. †
Agata Y, †Matsuda E, Sugai M, Katakai T, Gonda H, Shimizu A. (†co-first author)
Targeting of Krüppel-associated box-containing zinc finger proteins to centromeric heterochromatin. Implication for the gene silencing mechanisms.
J. Biol. Chem., 276, 14222-14229 (2001)

34.
Agata Y, Matsuda E, Shimizu A.
Two novel Krüppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 (TIF1β/KRIP-1).
J. Biol. Chem., 274, 16412-16422 (1999)

35.
Agata Y, Matsuda E, Shimizu A.
Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.
Gene 213, 55-64 (1998)

36. Katakai T,
Agata Y, Shimizu A, Ohshima C, Nishio A, Inaba M, Kasakura S, Mori KJ, Masuda T.
Structure of T cell receptor expressed on a gastritogenic T cell clone, II-6, and frequent appearance of the similar clonotypes in mice bearing autoimmune gastritis.
Int. Immunol., 9, 1849-1855 (1997)

37. Nishimura H,
Agata Y, Kawasaki A, Sato M, Imamura S, Minato N, Yagita H, Nakano T, Honjo T.
Developmentally Regulated Expression of the PD-1 Antigen on the Surface of the Double Negative (CD4- CD8-) Thymocytes.
Int. Immunol., 8, 773-780 (1996)

38.
Agata Y, Kawasaki A, Nishimura H, Ishida Y, Tsubata T, Yagita H, Honjo T.
Expression of the PD-1 Antigen on the Surface of Stimulated Mouse T and B Lymphocytes.
Int. Immunol., 8, 765-772 (1996)

39. Ishida Y,
Agata Y, Shibahara K, Honjo T.
Induced Expression of PD-1, a Novel Member of the Immunoglobulin Gene Superfamily, upon Programmed Cell Death.
EMBO J., 11, 3887-3895 (1992)


総説
1.
縣 保年
抗原受容体遺伝子再構成におけるエピジェネティクス制御
炎症と免疫, 23(3), 31(227)-34(230) (2015)

2.
縣 保年
転写因子E2ATCRβ遺伝子の対立遺伝子排除
医学のあゆみ, 228(11), 1126-1127 (2009)

3.
田中裕之、山本篤、石田哲夫、堀池喜八郎
脊椎動物における
D-セリンデヒドラターゼの発見と哺乳類におけるその欠損
蛋白質核酸酵素, 54, 1190-1196 (2009)

4.
縣 保年
E2A
T細胞抗原受容体遺伝子の再構成と対立遺伝子排除を制御する
細胞工学, 27(3), 258-259 (2008)

5. Tanaka H, Yamamoto A, Ishida T, Horiike K.
D-Serine is degraded to 3-hydroxypyruvate, not pyruvate, in the rat brain
stem and cerebellum homogenates.
In "Flavins and Flavoproteins 2008" (Frago S. et al. ed.) Prensas Universitarias
de Zaragoza, Zaragoza, Spain,
521-524 (2008)

6. Yamamoto A,
Tanaka H, Ishida T, Horiike K.
Substrate activation of D-aspartate oxidase from porcine kidney.
In "Flavins and Flavoproteins 2008" (Frago S. et al. ed.) Prensas Universitarias
de Zaragoza, Zaragoza, Spain,
69-73 (2008)

7. 縣 保年
遺伝子再編成におけるクロマチンのダイナミクス
蛋白質核酸酵素, 51(4), 315-325 (2006)

8.
縣 保年
クロマチン修飾によるTリンパ球の抗原レセプター遺伝子組換え制御
分子細胞治療, 3(2), 203-211 (2004)

9.
生田宏一, Ye, S.K., 李海天, 縣 保年
IL-7
レセプターシグナルによるTCRγ遺伝子座の組換え制御
Annual Review 免疫2002, 168-173 (2002)

10.
縣 保年, 生田宏一
ヒストンのアセチル化による抗原レセプター遺伝子組換え制御
臨床免疫36(6), 895-909 (2001)

11.
縣 保年, 生田宏一
クロマチン修飾とリモデリングによる抗原レセプター遺伝子組換え制御
実験医学19(16), 2171-2178 (2001)