神経難病研究センター 創薬研究部門 滋賀医科大学

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What's going on

2020/02/18
A research paper from our lab, describing the juvenile transcriptome and age-dependent alternative splicing (ADAS), was accepted !NEW
2019/08/16
High school student stayed in our lab
2019/07/31
Research grant for young investigators in Shiga University of Medical Science (SUMS)
2019/07/18
We attended the 4th conference of the Scientific Research on Innovative Areas, “Interplay of developmental clock and extracellular environment in brain formation” held in Kanazawa.
2019/03/05
Our paper, describing the juvenility-associated lncRNAs (Jalncs), was accepted !
2018/12/10
SUMS symposium
2018/11/06
Presented at SfN (Neuroscience 2018 San Diego)
2017/05/02
Laboratory report

Welcome to the Mori lab-page at the MNRC.


I am Masaki Mori, a pediatrician-scientist,
the principal investigator of Department of Medical Chemistry,
Shiga University of Medical Science (SUMS).

The primary aim of the lab is to find a solution for pediatric intractable diseases.

For that purpose, we are currently engaged in molecular biological approach,
bioinformatics and disease modeling.

We are welcoming graduate students who are interested in our research.
Contact us anytime [contact information is as below].


The projects in the lab are:

◆ Pediatrics molecular medicine

Aiming at understanding and finding a solution for pediatric diseases, we have been engaged in the elucidation of molecular basis for the uniqueness that only children possess, and adult don’t.


◆ Cell competition

How do cells dialogue?
We are studying a role of the cell competition in the cellular quality control in the organs.


◆ Physical aspect of a cell: Microrheology

(Collaboration with Dr. Daisuke Mizuno, Kyusyu university.)

Is physical status of a cell (stiffness, for example) affected by biological factors? How?
Thanks to the fruitful collaboration with Dr. Daisuke Mizuno, Kyusyu university, we are tackling to uncover the unsolved questions of life.


◆ Bioinformatics

How thousands of factors behave in a cell?
By computational biology, we are addressing how the network of genes and molecules dynamically behave.


◆ Human genetic disease modeling.

Utilizing CRISPR-Cas9 genome editing system, we are producing and analyzing the models of human diseases.
Therapeutic ideas are being sought.



Thank you very much for visiting our lab page.


[Contact]
Masaki Mori (morim[at]belle.shiga-med.ac.jp)
Principal investigator

Department of Medical Chemistry
Molecular Neuroscience Research Center (MNRC)
Shiga University of Medical Science (SUMS)
Address: Tsukinowa-cho, Seta, Otsu, Shiga, Japan, 520-2192
Phone: +81-77-548-2327
Fax: +81-77-548-2331