Original articles(2011~present) 


Abdullah A, Hayashi Y, Morimura N, Hitoshi S (2024) Role of α1,3-fucosyltransferases in the mammalian brain and their association with neuropsychiatric disorders. Trend Glycosci Glycotechnol in press        


Zak ZMM, Kuroda A,Morimura N, Hayashi Y, Hitoshi S (2023) Depletion of transit amplifying cells in the adult brain does not affect quiescent neural stem cell pool size. J Physiol Sci 17, 19        PubMed|Journal


Abdullah A, Hayashi Y, Morimura N, Kumar A, Ikenaka K, Togayachi A, Narimatsu H, Hitoshi S (2022) Fut9 deficiency causes abnormal neural development in the specific layer of the brain and retina. Neurochem Res 47, 2793–2804        PubMed|Journal


Oura S, Noda T, Morimura N, Hitoshi S, Nishimasu H, Nagai Y, Nureki O, Ikawa M (2021) Precise CAG repeat contraction in a Huntington’s Disease mouse model is enabled by gene editing with SpCas9-NG.
Commun Biol 4, 771        PubMed|Journal


*Tanaka A, *Ishida S, *Fuchigami T, Hayashi Y, Kuroda A, Ikenaka K, Hitoshi S (2020) Life-long neural stem cells are fate-specified at an early developmental stage. (*, equal contribution)
Cerebral Cortex 30, 6415–6425        PubMed|Journal

Daun KA, Fuchigami T, Koyama N, Maruta N, Ikenaka K, Hitoshi S (2020) Early maternal and social deprivation expands neural stem cell population size and reduces hippocampus/amygdala-dependent fear memory.
Front Neurosci 14, 22        PubMed|Journal


Seita Y, Tsukiyama T, Azami T, Kobayashi K, Iwatani C, Tsuchiya H, Nakaya M, Tanabe H, Hitoshi S, Miyoshi H, Nakamura S, Kawauchi A, Ema M (2019) Comprehensive evaluation of ubiquitous promoters suitable for the generation of transgenic cynomolgus monkeys.
Biol Reprod 100, 1440-1452        PubMed|Journal


*Hayashi Y, *Jinnou H, Sawamoto K, Hitoshi S (2018) Adult neurogenesis and its role in brain injury and psychiatric diseases. (*, equal contribution)
J Neurochem 147, 584-594        PubMed|Journal

Kuroda A, Fuchigami T, Fuke S, Koyama N, Ikenaka K, Hitoshi S (2018) Minocycline directly enhances the self-renewal of adult neural precursor cells.
Neurochem Res 43, 219-226        PubMed|Journal


Morimura N, Yasuda H, Yamaguchi K, Katayama KI, Hatayama M, Tomioka NH, Odagawa M, Kamiya A, Iwayama Y, Maekawa M, Nakamura K, Matsuzaki H, Tsujii M, Yamada K, Yoshikawa T, Aruga J (2017) Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice.
Nature Communications 8, 15800        PubMed|Journal

Naruse M, Ishizaki Y, Ikenaka K, Tanaka A, Hitoshi S (2017) Origin of oligodendrocytes in mammalian forebrains: a revised perspective.
J Physiol Sci 67, 63-70        PubMed|Journal


Seita Y, Tsukiyama T, Iwatani-Tsuchiya C, Tsuchiya H, Matsushita J, Azami T, Okahara J, Nakamura S, Hayashi Y, Hitoshi S, Imamura T, Miyoshi H, Saitou M, Ogasawara K, Sasaki E, Ema M (2016) Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body.
Sci Rep 6, 24868        PubMed|Journal

Yamaguchi M, Seki T, Imayoshi I, Tamamaki N, Hayashi Y, Tatebayashi Y, Hitoshi S (2016) Neural stem cells and neuro/gliogeneis in the central nervous system: understanding the structural and functional plasticity of the developing, mature, and diseased brain.
J Physiol Sci 66, 197-206        PubMed|Journal

*Naruse M, *Ishino Y, Kumar A, Ono K, Takebayashi H, Yamaguchi M, Ishizaki Y, Ikenaka K, Hitoshi S (2016) The dorsoventral boundary of the germinal zone is a specialized niche for the generation of cortical oligodendrocytes during a restricted temporal window. (*, equal contribution)
Cerebral Cortex 26, 2800-2810        PubMed|Journal


Torii T, Yoshimura T, Narumi M, Hitoshi S, Takaki Y, Tsuji S, Ikenaka K (2014) Determination of major sialylated N-glycans and identification of branched sialylated N-glycans that dynamically change their content during development in the mouse cerebral cortex.
Glycoconj J 31, 671-683        PubMed|Journal

Fuke S, Kametani M, Yamada K, Kubota-Sakashita M, Kasahara T, Kujoth GC, Prolla TA, Hitoshi S, Kato T (2014) A heterozygous Polg mutation causes motor dysfunction due to mtDNA deletions.
Annals of Clinical and Translational Neurology 1, 909-920        PubMed|Journal

*Zheng L-S, *Hitoshi S, *Kaneko N, Takao K, Miyakawa T, Tanaka Y, Xia H, Kalinke U, Kudo K, Kanba S, Ikenaka K, Sawamoto K (2014) Mechanisms for interferon-α-induced depression and neural stem cell dysfunction. (*, equal contribution)
Stem Cell Reports 3, 74-83        PubMed|Journal

*Ishino Y, *Hayashi Y, Naruse M, Tomita K, Sanbo M, Fuchigami T, Fujiki R, Hirose K, Toyooka Y, Fujimori T, Ikenaka K, Hitoshi S (2014) Bre1a, a histone H2B ubiquitin ligase, regulates the cell cycle and differentiation of neural precursor cells. (*, equal contribution)
J Neurosci 34, 3067-3078         PubMed|Journal


Kumar A, Torii T, Ishino Y, Muraoka D, Yoshimura T, Togayachi A, Narimatsu H, Ikenaka K, Hitoshi S (2013) The Lewis X-related α1,3-fucosyltransferase, Fut10, is required for the maintenance of stem cell populations.
J Biol Chem 288, 28859-28868        PubMed|Journal

Deguchi A, Hitoshi S, Yoshimura T, Fujimoto I, Ikeda T, Ishii A, Higashi M, Masaki T, Kuriyama S, Ikenaka K (2013) GnT V-catalyzed N-glycan products are not increased in hepatomas.
J Glycomics Lipidomics S5:003        

Shimizu T, Tanaka KF, Takebayashi H, Higashi M, Ono K, Hitoshi S, Ikenaka K (2013) Olig2-lineage cells preferentially differentiate into oligodendrocytes but fail to survive in the chronic demyelinating lesion.
J Neurosci Res 91, 178-186        PubMed|Journal


Iwashita N, Nosaka S, Koyama N (2012) Involvement of peripheral NMDA receptor in melittin-induced thermographic flare.
Neurochem Res 37, 2222-2228        PubMed|Journal

Tatebayashi Y, Nihonmatsu-Kikuchi N, Hayashi Y, Yu X, Soma M, Ikeda K. (2012) Abnormal fatty acid composition in the frontopolar cortex of patients with affective disorders.
Transl Psychiatry 2, e204        PubMed|Journal

Hayashi Y, Nihonmatsu-Kikuchi N, Hisanaga S-i, Yu X, Tatebayashi Y. (2012) Neuropathological similarities and differences between schizophrenia and bipolar disorder : a flow cytometric postmortem brain study.
PLoS One 7, e33019        PubMed|Journal


Hitoshi S, Ishino Y, Kumar A, Jasmine S, Tanaka KF, Kondo T, Kato S, Hosoya T, Hotta Y, Ikenaka K (2011) Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells.
Nat Neurosci 14, 957-964        PubMed|Journal

Fuke S, Kubota-Sakashita M, Kasahara T, Shigeyoshi Y, Kato T. (2011) Regional variation in mitochondrial DNA copy number in mouse brain.
Biochim Biophys Acta – Bioenergetics 1807, 270-274        PubMed|Journal

Hayashi Y, Nihonmatsu-Kikuchi N, Hisanaga S-i, Tatebayashi Y. (2011) A novel, rapid, cell-counting method for unfixed frozen brains comprehensively quantifies at least four neural cell populations.
Mol Psychiat 16, 1155        PubMed|Journal

Kato S, Kuramochi M, Takasumi K, Kobayashi K, Inoue KI, Takahara D, Hitoshi S, Ikenaka K, Shimada T, Takada M, Kobayashi K (2011) Neuron-Specific Gene Transfer through Retrograde Transport of Lentiviral Vector Pseudotyped with a Novel Type of Fusion Envelope Glycoprotein.
Hum Gene Ther 22, 1511-1523        PubMed|Journal

Kamitani-Kawamoto A, Hamada M, Moriguchi T, Miyai M, Saji F, Hatamura I, Nishikawa K, Takayanagi H, Hitoshi S, Ikenaka K, Hosoya T, Hotta Y, Takahashi S, Kataoka K (2011) MafB interacts with Gcm2 and regulates parathyroid hormone expression and parathyroid development.
J Bone Miner Res 26, 2463-2472        PubMed|Journal