Original articles(~2000) 


Koyama N, Nishio T, Yokota T (2000) Non-serotonergic midbrain neurons are involved in picrotoxin-induced analgesia. An immunohistochemical study in the rat.
Neurosci Lett 291, 147-150         PubMed|Journal

Koyama N, Hirata K, Hori K, Dan K, Yokota T (2000) Computer-assisted infrared thermographic study of axon reflex induced by intradermal melittin.
Pain 84, 133-139         PubMed|Journal


Hitoshi S, Kusunoki S, Murayama S, Tsuji S, Kanazawa I (1999) Rabbit experimental sensory ataxic neuropathy; anti-GD1b antibody-mediated trkC downregulation of dorsal root ganglia neurons.
Neurosci Lett 260, 157-160         PubMed|Journal

Hitoshi S, Kusunoki S, Kanazawa I, Tsuji S (1999) Dorsal root ganglia neuron-specific promoter activity of the rabbit β-galactoside α1,2-fucosyltransferase gene.
J Biol Chem 274, 389-396        PubMed|Journal

Kusunoki S, Hitoshi S, Kaida K-I, Arita M, Kanazawa I (1999) Monospecific anti- GD1b IgG is required to induce rabbit ataxic neuropathy.
Ann Neurol 45, 400-403          PubMed|Journal

Kusunoki S, Hitoshi S, Kaida K-I, Murayama S, Kanazawa I (1999) Degeneration of rabbit sensory neurons induced by passive transfer of anti-GD1b antiserum.
Neurosci Lett 273, 33-36         PubMed|Journal

Nishikawa Y, Koyama N, Yoshida Y, Yokota T (1999) Activation of ascending antinociceptive system by vagal afferent input as revealed in the nucleus ventralis posteromedialis.
Brain Res 833, 108-111         PubMed|Journal


Hitoshi S, Kusunoki S, Kanazawa I, Tsuji S (1998) Dorsal root ganglia-specific expression of the β-galactoside α1,2-fucosyltransferase genes in rabbits.
J Neurochem 70, 2174-2178         PubMed|Journal

Koyama N, Nishikawa Y, Yokota T (1998) Distribution of nociceptive neurons in the ventrobasal complex of macaque thalamus.
Neurosci Res 31, 39-51         PubMed|Journal

Koyama N, Hanai F, Yokota T (1998) Does intravenous administration of GABA(A) receptor antagonists induce both descending antinociception and touch-evoked allodynia?
Pain 76, 327-336         PubMed|Journal

Chen J, Koyama N (1998) Differntial activation of spinal dorsal horn units by subcutaneous formalin injection in the cat: an electrophysiological study.
Exp Brain Res 118, 14-18         PubMed|Journal


Kusunoki S, Mashiko H, Mochizuki N, Chiba A, Arita M, Hitoshi S, Kanazawa I (1997) Binding of antibodies against GM1 and GD1b in human peripheral nerve.
Muscle Nerve 20, 840-845         PubMed|Journal

Osada A, Fujino Y, Chen J, Koyama N (1997) Differential effects of ketamine and MK-801 on A-fiber and C-fiber responses of spinal wide dynamic range neurons in the cat.
J Anesthesia 11, 184-192         Journal

Chen J, Koyama N, Kaneko T, Mizuno N (1997) The locus coeruleus of the Japanese monkey (Macaca fuscata) does not express m-opioid receptor-like immunoreactivety. (1998) Differntial activation of spinal dorsal horn units by subcutaneous formalin injection in the cat: an electrophysiological study.
Brain Res 755, 326-330         PubMed|Journal


Hitoshi S, Kusunoki S, Kanazawa I, Tsuji S (1996) Molecular cloning and expression of a third type of rabbit α1,2-fucosyltransferase.
J Biol Chem 271, 16975-16981         PubMed|Journal

Hitoshi S, Kusunoki S, Kon K, Chiba A, Waki H, Ando S, Kanazawa I (1996) A novel ganglioside, 9-O-acetyl GD1b, is recognized by serum antibodies in Guillain-Barré syndrome.
J Neuroimmunol 66, 95-101         PubMed|Journal

Kusunoki S, Shimizu J, Chiba A, Ugawa Y, Hitoshi S, Kanazawa I (1996) Experimental sensory neuropathy induced by sensitization with ganglioside GD1b.
Ann Neurol 39, 424-431         PubMed|Journal

Kusunoki S, Iwamori M, Chiba, A, Hitoshi S, Arita M, Kanazawa I (1996) GM1b is a new member of antigen for surem antibody in Guillain-Barré syndrome.
Neurology 47, 237-242         PubMed|Journal

Kuwabara K, Hitoshi S, Nukina N, Ishii K, Momose T. Kubota S, Seyama Y., Kanazawa I (1996) PET analysis of a case of cerebrotendinous xanthomatosis presenting hemiparkinsonism.
J Neurol Sci 138, 145-149         PubMed|Journal

Hitoshi S, Kojima N, Kusunoki S, Inokuchi J, Kanazawa I, Tsuji S (1996) Expression of the β-galactoside α1,2-fucosyltransferase gene suppresses axonal outgrowth of Neuro2a neuroblastoma cells.
J Neurochem 66, 1633-1640         PubMed|Journal

Tsuji S, Kojima N, Hitoshi S (1996) New evidence for the occurrence of a glycolipid-mediated signal transduction system.
J Lipid Mediat Cell Signal 14, 289-294         PubMed|Journal


Hitoshi S, Kusunoki S, Kanazawa I, Tsuji S (1995) Molecular cloning and expression of two types of rabbit β-galactoside α1,2-fucosyltransferase.
J Biol Chem 270, 8844-8850         PubMed|Journal

Kusunoki S, Chiba, A, Hitoshi S, Takizawa, H, Kanazawa I (1995) Anti-Gal-C antibody in autoimmune neuropathies subsequent to Mycoplasma infection.
Muscle Nerve 18, 409-413         PubMed|Journal


Hitoshi S, Kusunoki S, Chiba A, Takatsu R, Sunada Y, Nukina N, Tai T, Kanazawa I (1994) Cerebeller ataxia and polyneuropathy in a patient with IgM M-protein specific to the Gal(β1-3)GalNAc epitope.
J Neurol Sci 126, 219-224         PubMed|Journal

Hitoshi S, Suzuki K, Sakuta M (1994) Elevated serum interleukin-6 in POEMS syndrome reflects the activity of the disease.
Intern Med 33, 583-587         PubMed|Journal


Hitoshi S, Nagura H, Yamanouchi H, Kitamoto T (1993) Double mutations at codon 180 and codon 232 of the PRNP gene in an apparently sporadic case of Creutzfeldt-Jakob disease.
J Neurol Sci 120, 208-212         PubMed|Journal

Kitamoto T, Ohta M, Doh-ura K, Hitoshi S, Terao Y, Tateishi J (1993) Novel missense variants of prion protein in Creutzfeldt-Jakob disease or Gerstmann-Sträussler syndrome.
Biochem Biophys Res Commun 191, 709-714         PubMed|Journal

Hitoshi S, Terao Y, Sakuta M (1993) Portal-systemic encephalopathy and hypothalamic hypothyroidism: effect of thyroid hormone on ammonia metabolism.
Intern Med 32, 655-658         PubMed|Journal


Hitoshi S, IwataM, Yoshikawa K (1991) Midbrain pathology of Wilson's disease: MRI analysis of three cases.
J Neurol Neurosurg Psychiat 54, 624-626         PubMed|Journal

Hitoshi S, Ito Y, Takehara K, Fujita T, Ogata E (1991) A case of malignant hypertension and scleroderma after cosmetic surgery.
Jpn J Med 30, 97-100         PubMed|Journal


Original articles




Books & Reviews


Prof. Seiji Hitoshi

Seta Tsukinowa-cho
Otsu, Shiga 520-2192

TEL: +81-77-548-2148
FAX: +81-77-548-2146