Ikuo Tooyama

CV

EDUCATION:
1975-1981 Faculty of Medicine, Kyoto University, Japan
1981 Award of the degree of M.D. (Kyoto University)
1981 National Board of Medical Doctor
1984-1988 Graduate School in Faculty of Medicine, Kyoto University, Japan
1985 Japan Board of Neurology
1988 Award of the degree of Ph. D. (Kyoto University) PROFESSIONAL APPOINTMENTS:
1988-1989 Research Associate at Department of Anatomy Shiga University of Medical Science
1989-1991 Research Associate at Institute of Molecular Neurobiology, Shiga University of Medical Science 1991-1992 Visiting Scientist at Kinsmen Laboratory of Neurological Research The University of British Columbia, Canada
1992-1995 Research Associate at Institute of Molecular Neurobiology, Shiga University of Medical Science 1995- 1999 Associate Professor at Institute of Molecular Neurobiology, Shiga University of Medical Science 1999-present Professor at Molecular Neuroscience Research Center Shiga University of Medical Science 2010-present Director at Molecular Neuroscience Research Center Shiga University of Medical Science

・Consultant to government Consultant to Shiga Bio-Industry Organization (SBO) of Shiga Prefecture
(2006 – present)
・Director-president etc of scientific societies etc A member of the board of directors of Japan Brain Science Society (2003 – present)
・A member of the board of directors of Japan Society for Dementia Research (2011 – present)
・Journal editor or editorial board Editorial Board of Acta Histochemica et Cytochemica (2012-present)
・Editorial Board of Jounral of Alzheimer's Disease (2012-present)

Message

We very welcome to accept foreign students and visiting scientists in the MNRC. The MNRC consists of five research units and about 30 researchers and students are working in the center. The MNRC gets grants of about half million dollars per year. In order to obtain fruitful results, we collaborate with Biomedical MR Center, Center for Animal Life Science as well as departments in Faculty of Medicine and University Hospitals and we have organized Research Promotion Organization for Intractable Neurological Disease. We very welcome the collaborations with other laboratories in the world.We very welcome to accept foreign students and visiting scientists in the MNRC.

Publication

1. Alpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer's disease patients. Kato T, Konishi Y, Shimohama S, Beach TG, Akatsu H, Tooyama I Neuroscience letters 591 19-24 Mar. 2015

2. Upregulation of mitochondrial ferritin by proinflammatory cytokines: implications for a role in Alzheimer's disease. Yang H, Guan H, Yang M, Liu Z, Takeuchi S, Yanagisawa D, Vincent SR, Zhao S, Tooyama I Journal of Alzheimer's disease : JAD 45(3) 797-811 Jan. 2015

3. Curcumin derivative with the substitution at C-4 position, but not curcumin, is effective against amyloid pathology in APP/PS1 mice. Yanagisawa D, Ibrahim NF, Taguchi H, Morikawa S, Hirao K, Shirai N, Sogabe T, Tooyama I Neurobiology of aging 36(1) 201-210 Jan. 2015

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