Prof. Seiji Hitoshi, M.D., Ph.D.

hitoshi


Education

1988          : M. D., Fuculty of Medicine, University of Tokyo
1997          : Ph. D., Graduate School of Medicine, University of Tokyo

Professional Appointments

2011-         : Professor, Department of Integrative Physiology, Shiga University of
                        Medical Science
2003-2011 : Associate Professor, National Institute for Physiological Sciences
2001-2003 : Assistant Professor, Department of Neurology, University of Tokyo
1999-2001 : Postdoctoral Fellow, Department of Anatomy and Cell Biology
                        University of Toronto
1997-1999 : Special Postdoctoral Researcher, the Institute of Physical and Chemical
                        Research (RIKEN)
1992-1993 : Neurologist, Tokyo University Hospitals
1991-1992 : Neurologist, Tokyo Metropolitan Geriatric Medical Center
1990-1991 : Neurologist, Japan Red Cross Medical Center
1988-1990 : Resident physician, Tokyo University Affiliated Hospitals

Research Interest

Developmantal Neurobiology; Adult Neurogenesis and Neurological and Psychiatric Diseasses, Autoimmune Neurological Diseases

Selected publications

  • Hitoshi S, Ishino Y, Kumar A, Jasmine S, Tanaka KF, Kondo T, Kato S, Hosoya T, Hotta Y, Ikenaka K. (2011) Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells. Nat Neurosci 14, 957-964
  • Hitoshi S, Alexon T, Tropepe V, Donoviel D, Elia AJ, Nye JS, Conlon RA, Mak TW, Bernstein A, van der Kooy D. (2002) Notch pathway molecules are essential for the maintenance, but not for the generation, of mammalian neural stem cells. Genes & Dev. 16, 846-858
  • Hitoshi S, Kusunoki S, Kanazawa I, Tsuji S. (1995) Molecular cloning and expression of two types of rabbit β-galactoside α1,2-fucosyltransferase. J Biol Chem 270, 8844-8850
  • Hitoshi S, Iwata M, Yoshikawa K. (1991) Midbrain pathology of Wilson's disease: MRI analysis of three cases. J Neurol Neurosurg Psychiat 54, 624-626

Address

Seta Tsukinowa-cho
Otsu, Shiga 520-2192
Japan
TEL: +81-77-548-2148
FAX: +81-77-548-2146