Espinosa-Jeffrey A, Hitoshi S, Zhao P, Awosika O, Agbo C, Olaniyan E, Garcia J, Valera R, Thomassian A, Chang-Wei R, Yamaguchi M, de Vellis J, Ikenaka K (2010) Functional central nervous system myelin repair in an adult mouse model of demyelination caused by proteolipid protein overexpression.
J Neurosci Res 88, 1682-1694 PubMed|Journal
Ema M, Mori D, Niwa H, Hasegawa Y, Yamanaka Y, Hitoshi S, Mimura J, Kawabe Y, Hosoya T, Morita M, Shimosato D, Uchida K, Suzuki N, Yanagisawa J, Sogawa K, Rossant J, Yamamoto M, Takahashi S, Fujii-Kuriyama Y (2008) Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs.
Cell Stem Cell 3, 555-567 PubMed|Journal
Higashi M, Maruta N, Bernstein A, Ikenaka K, Hitoshi S (2008) Mood stabilizing drugs expand the neural stem cell pool in the adult brain through activation of Notch signaling.
Stem Cells 26, 1758-1767 研究紹介|PubMed|Journal
Sasaki N, Okishio K, Ui-Tei K, Saigo K, Kinoshita-Toyoda A, Toyoda H, Nishimura T, Suda Y, Hayasaka M, Hanaoka K, Hitoshi S, Ikenaka K, Nishihara S (2008) Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells.
J Biol Chem 283, 3594-3606 PubMed|Journal
Fuke S, Kametani M, Kato T. (2008) Quantitative analysis of the 4977-bp common deletion of mitochondrial DNA in postmortem frontal cortex from patients with bipolar disorder and schizophrenia.
Neurosci Lett 439, 173-177 PubMed|Journal
Hitoshi S, Maruta N, Higashi M, Kumar A, Kato N, Ikenaka K (2007) Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress.
J Neurosci Res 85, 3574-3585 研究紹介|PubMed|Journal
Karpowicz P, Inoue T, Runciman S, Deveale B, Seaberg R, Gertsenstein M, Byers L, Yamanaka Y, Tondat S, Slevin J, Hitoshi S, Rossant J, van der Kooy D (2007) Adhesion is prerequisite, but alone insufficient, to elicit stem cell pluripotency.
J Neurosci 27, 5437-5447 PubMed|Journal
Ishii A, Ikeda T, Hitoshi S, Fujimoto I, Torii T, Sakuma K, Nakakita SI, Hase S, Ikenaka K (2007) Developmental Changes in the Expression of Glycogenes and the Content of N-glycans in the Mouse Cerebral Cortex.
Glycobiology 17, 261-276 PubMed|Journal
Hasegawa A, Naruse M, Hitoshi S, Iwasaki Y, Takebayashi H & Ikenaka K (2007) Regulation of glial development by cystatin C.
J Neurochem 100, 12-22 PubMed|Journal
Wada T, Haigh JJ, Ema M, Hitoshi S, Chaddah R, Rossant J, Nagy A, van der Kooy D (2006) Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival.
J Neurosci 26, 6803-6812 PubMed|Journal
Naruse M, Nakahira E, Miyata T, Hitoshi S, Ikenaka K, Bansal R (2006) Induction of oligodendrocyte progenitors in dorsal forebrain by intraventricular microinjection of FGF-2.
Dev Biol 297, 262-273 PubMed|Journal
Alexson TO, Hitoshi S, Coles BL, Bernstein A, van der Kooy D (2006) Notch signaling is required to maintain all neural stem cell populations--irrespective of spatial or temporal niche.
Dev Neurosci 28, 34-48 PubMed|Journal
Sakuma K, Fujimoto I, Hitoshi S, Tanaka F, Ikeda T, Tanabe K, Toyokuni S, Wada H, Mio T, Mishima M, Ikenaka K (2006) An N-glycan structure correlates with pulmonary metastatic ability of cancer cells.
Biochem Biophys Res Commun 340, 829-835 PubMed|Journal
Kitagawa J, Kanda K, Sugiura M, Tsuboi Y, Ogawa A, Shimizu K, Koyama N, Kamo H, Watanabe T, Ren K, Iwata K (2005) Effect of Chronic Inflammation on Dorsal Horn Nociceptive Neurons in Aged Rats.
J Neurophysiol 93, 3594-3604 PubMed|Journal
Hitoshi S, Seaberg RM, Koscik C, Alexson T, Kusunoki S, Kanazawa I, Tsuji S, van der Kooy D (2004) Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling.
Genes & Dev 18, 1806-1811 研究紹介|PubMed|Journal
Kusunoki S, Morita D, Ohminami S, Hitoshi S, Kanazawa I (2003) Binding of IgG antibodies in GBS sera to a mixture of GM1 and a phospholipid: possible clinical implications.
Muscle Nerve 27, 302-306 PubMed|Journal
Hitoshi S, Alexon T, Tropepe V, Donoviel D, Elia AJ, Nye JS, Conlon RA, Mak TW, Bernstein A, van der Kooy D (2002) Notch pathway molecules are essential for the maintenance, but not for the generation, of mammalian neural stem cells.
Genes & Dev 16, 846-858 研究紹介|PubMed|Journal
Hitoshi S, Tropepe V, Sirard C, Ekker M, van der Kooy D (2002) Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain.
Development 129, 233-244 研究紹介|PubMed|Journal
Koyama N, Hirata K, Hori K, Dan K, Yokota T (2002) Biphasic vasomotor reflex responses of the hand skin following intradermal injection of melittin into the forearm skin.
Eur J Pain 6, 447-453 PubMed|Journal
Tropepe V, Hitoshi S, Sirard C, Mak TW, Rossant J, van der Kooy D (2001) Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism.
Neuron 30, 65-78 研究紹介|PubMed|Journal
Ichikawa K, Koyama N, Kiguchi S, Kojima M, Yokota T (2001) Inhibitory effect of oxcarbazepine on high-frequency firing in peripheral nerve fibers.
Eur J Pharmacol 420, 119-122 PubMed|Journal