英文原著論文(2001年~2010年) 

2010年 

Espinosa-Jeffrey A, Hitoshi S, Zhao P, Awosika O, Agbo C, Olaniyan E, Garcia J, Valera R, Thomassian A, Chang-Wei R, Yamaguchi M, de Vellis J, Ikenaka K (2010) Functional central nervous system myelin repair in an adult mouse model of demyelination caused by proteolipid protein overexpression.
J Neurosci Res 88, 1682-1694        PubMed|Journal

2008年 

Ema M, Mori D, Niwa H, Hasegawa Y, Yamanaka Y, Hitoshi S, Mimura J, Kawabe Y, Hosoya T, Morita M, Shimosato D, Uchida K, Suzuki N, Yanagisawa J, Sogawa K, Rossant J, Yamamoto M, Takahashi S, Fujii-Kuriyama Y (2008) Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs.
Cell Stem Cell 3, 555-567        PubMed|Journal

Higashi M, Maruta N, Bernstein A, Ikenaka K, Hitoshi S (2008) Mood stabilizing drugs expand the neural stem cell pool in the adult brain through activation of Notch signaling.
Stem Cells 26, 1758-1767        研究紹介|PubMed|Journal

Sasaki N, Okishio K, Ui-Tei K, Saigo K, Kinoshita-Toyoda A, Toyoda H, Nishimura T, Suda Y, Hayasaka M, Hanaoka K, Hitoshi S, Ikenaka K, Nishihara S (2008) Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells.
J Biol Chem 283, 3594-3606        PubMed|Journal

Fuke S, Kametani M, Kato T. (2008) Quantitative analysis of the 4977-bp common deletion of mitochondrial DNA in postmortem frontal cortex from patients with bipolar disorder and schizophrenia.
Neurosci Lett 439, 173-177        PubMed|Journal

2007年 

Hitoshi S, Maruta N, Higashi M, Kumar A, Kato N, Ikenaka K (2007) Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress.
J Neurosci Res 85, 3574-3585        研究紹介|PubMed|Journal

Karpowicz P, Inoue T, Runciman S, Deveale B, Seaberg R, Gertsenstein M, Byers L, Yamanaka Y, Tondat S, Slevin J, Hitoshi S, Rossant J, van der Kooy D (2007) Adhesion is prerequisite, but alone insufficient, to elicit stem cell pluripotency.
J Neurosci 27, 5437-5447        PubMed|Journal

Ishii A, Ikeda T, Hitoshi S, Fujimoto I, Torii T, Sakuma K, Nakakita SI, Hase S, Ikenaka K (2007) Developmental Changes in the Expression of Glycogenes and the Content of N-glycans in the Mouse Cerebral Cortex.
Glycobiology 17, 261-276        PubMed|Journal

Hasegawa A, Naruse M, Hitoshi S, Iwasaki Y, Takebayashi H & Ikenaka K (2007) Regulation of glial development by cystatin C.
J Neurochem 100, 12-22        PubMed|Journal

2006年 

Wada T, Haigh JJ, Ema M, Hitoshi S, Chaddah R, Rossant J, Nagy A, van der Kooy D (2006) Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival.
J Neurosci 26, 6803-6812        PubMed|Journal

Naruse M, Nakahira E, Miyata T, Hitoshi S, Ikenaka K, Bansal R (2006) Induction of oligodendrocyte progenitors in dorsal forebrain by intraventricular microinjection of FGF-2.
Dev Biol 297, 262-273        PubMed|Journal

Alexson TO, Hitoshi S, Coles BL, Bernstein A, van der Kooy D (2006) Notch signaling is required to maintain all neural stem cell populations--irrespective of spatial or temporal niche.
Dev Neurosci 28, 34-48        PubMed|Journal

Sakuma K, Fujimoto I, Hitoshi S, Tanaka F, Ikeda T, Tanabe K, Toyokuni S, Wada H, Mio T, Mishima M, Ikenaka K (2006) An N-glycan structure correlates with pulmonary metastatic ability of cancer cells.
Biochem Biophys Res Commun 340, 829-835        PubMed|Journal

2005年 

Kitagawa J, Kanda K, Sugiura M, Tsuboi Y, Ogawa A, Shimizu K, Koyama N, Kamo H, Watanabe T, Ren K, Iwata K (2005) Effect of Chronic Inflammation on Dorsal Horn Nociceptive Neurons in Aged Rats.
J Neurophysiol 93, 3594-3604        PubMed|Journal

2004年 

Hitoshi S, Seaberg RM, Koscik C, Alexson T, Kusunoki S, Kanazawa I, Tsuji S, van der Kooy D (2004) Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling.
Genes & Dev 18, 1806-1811        研究紹介|PubMed|Journal

2003年 

Kusunoki S, Morita D, Ohminami S, Hitoshi S, Kanazawa I (2003) Binding of IgG antibodies in GBS sera to a mixture of GM1 and a phospholipid: possible clinical implications.
Muscle Nerve 27, 302-306        PubMed|Journal

2002年 

Hitoshi S, Alexon T, Tropepe V, Donoviel D, Elia AJ, Nye JS, Conlon RA, Mak TW, Bernstein A, van der Kooy D (2002) Notch pathway molecules are essential for the maintenance, but not for the generation, of mammalian neural stem cells.
Genes & Dev 16, 846-858         研究紹介|PubMed|Journal

Hitoshi S, Tropepe V, Sirard C, Ekker M, van der Kooy D (2002) Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain.
Development 129, 233-244        研究紹介|PubMed|Journal

Koyama N, Hirata K, Hori K, Dan K, Yokota T (2002) Biphasic vasomotor reflex responses of the hand skin following intradermal injection of melittin into the forearm skin.
Eur J Pain 6, 447-453         PubMed|Journal

2001年 

Tropepe V, Hitoshi S, Sirard C, Mak TW, Rossant J, van der Kooy D (2001) Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism.
Neuron 30, 65-78         研究紹介|PubMed|Journal

Ichikawa K, Koyama N, Kiguchi S, Kojima M, Yokota T (2001) Inhibitory effect of oxcarbazepine on high-frequency firing in peripheral nerve fibers.
Eur J Pharmacol 420, 119-122         PubMed|Journal

 

原著論文

2011年~現在

2001年~2010年

           ~2000年

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〒520-2192
滋賀県大津市瀬田月輪町
滋賀医科大学
統合臓器生理学部門
TEL: 077-548-2148
FAX: 077-548-2146

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